Cloned (Comment) | Organism |
---|---|
expression in CHO cells | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of KSST suppresses the expression of sialyl Lewis X on CHO cells engineered to express sialyl Lewis X, KSST expression in those cells suppresses lymphocyte rolling compared with mock-transfected CHO cells expressing 6-sulfo sialyl Lewis X, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + keratan | Mus musculus | - |
adenosine 3',5'-bisphosphate + keratan 6'-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + N-acetyllactosamine | Mus musculus | - |
adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine | - |
? | |
additional information | Mus musculus | KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymph node | peripheral | Mus musculus | - |
lymphocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + keratan | - |
Mus musculus | adenosine 3',5'-bisphosphate + keratan 6'-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + N-acetyllactosamine | - |
Mus musculus | adenosine 3',5'-bisphosphate + 6'-sulfo N-acetyllactosamine | - |
? | |
additional information | KSST competes with fucosyltransferase-VII for the same acceptor substrate and downregulates the synthesis of L-selectin ligand by inhibiting alpha1,3-fucosylation, sulfated oligosaccharide, e.g. 6'-sulfated galactose residues, increase in FucT-VII-deficient mutant mice, structure of mono-sulfated O-glycans, detailed overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
keratan sulfate sulfotransferase | - |
Mus musculus |
KSST | - |
Mus musculus |